In good compliers, maximum walking distance and maximum walking time increased by 29.15% (0.0 to 66.7) and 33.3% (-20.0 to 50.0) respectively. The baseline IADL Score was significantly associated with good compliance to the prevention program (p=0.0011). The maximum walking time remained stable while decreasing by 25% in the control group (p=0.0015) and fewer participants had a worsened IADL score in the prevention group (p=0.05).
Twenty-three (44%) were good compliers for both interventions. Their median Activities of Daily Living and Instrumental Activities of Daily Living (IADL) scores were 6 and 7 respectively. One hundred and two persons (prevention n=53, control n=49) with a median age of 85 years were included. A linear regression model was fitted to assess the effect of the intervention on the relative variation of outcomes, adjusted for unbalanced baseline co-variables. Non-parametric methods were used for comparisons between the two groups. Main outcome measures included physical activity (the PASE questionnaire), functional tests, nutritional and autonomy scores, and compliance (50% or more was considered satisfactory). The intervention combined a self-administered exercise program, with 10 g amino-acid supplementation under the supervision of HHs.
The participants were all over 78 years old, lived independently at home, and received the visits of HHs at least once a week. Our main objective was to assess whether a home-based program supervised by home helpers (HH) during their normal working hours can prevent excessive sedentariness (mainly maximum walking time and distance) and preserve functional status in elderly people at risk for frailty or disability and using domestic services.Ī four-month, open label, randomised trial with two groups called "prevention" and "control".
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